ERBB2 and neoplasm: In addition, a significant association was detected between the HI ranks and the tumor subtype PAM50 classification, i.e.: 38/ 42 (90%) of basal like tumors presented “low” HI, while Luminal A and HER2 tumors were mostly equally distributed among “low” and “high” ranks; beside, more than the half (58%) of Luminal B tumors were included in the “high” range of HI (Table 3).