Most frequent treatment-emergent drug related adverse events (all grades) occurring in ≥10% of patients were diarrhea (n = 12; 55%), fatigue (n = 10; 45%), vomiting (n = 8; 36%), dry mouth (n = 6; 27%), decreased appetite (n = 6; 27%), dry skin (n = 5; 23%), hypophosphatemia (n = 4; 18%), stomatitis (n = 4; 18%), nausea (n = 4; 18%), dysgeusia (n = 4; 18%), hair color changes (n = 4; 18%), pyrexia (n = 3; 14%), increased ALT (n = 3; 14%), decreased weight (n = 3; 14%), alopecia (n = 3; 14%), and rashes (n = 3; 14%) (Table 3). The gene discussed is GPT; the disease is alopecia.