FGFR3 and neoplasm: UMUC14 and MGHU3 are representative of low grade and stage malignancies, in which FGFR3 mutation is more commonly found7, 97-7 is representative of FGFR3 mutant tumours with ability to invade the urothelial submucosa, and CAL29 is representative of the highest grade and stage tumours which often display FGFR3 upregulation rather than mutation7.