Our in vitro results show that activation of FGFR3 signalling in urothelial cells alters the expression of TAZ and two of its bona fide targets via ETV5, and are independently supported by the finding of an in vivo positive correlation between ETV5 and TAZ expression in two large publically available gene expression datasets from bladder tumours. Here, FGFR3 is linked to urinary bladder neoplasm.