Twenty-eight genes (Group I) were upregulated in DKD cells, including cyclin D1 (Ccnd1), serum/glucocorticoid regulated kinase 1 (Sgk1), adhesion G protein-coupled receptor G1 (Adgrg1), melanoma cell adhesion molecule (Mcam1), alkaline phosphatase, liver/bone/kidney (Alpl), and the WD-repeat domain phosphinositide-interacting protein 4 (Wdr45), a molecule associated with autophagy. This evidence concerns the gene SGK1 and diabetic kidney disease.