In the “A Long-Acting somatostatin on DIsease progression in Nephropathy due to autosomal dominant polycystic kidney disease” (ALADIN) trial, we compared octreotide-LAR for 3 years versus placebo in adults with ADPKD with normal kidney function or mild-to-moderate renal insufficiency (estimated glomerular filtration rate [eGFR] ≥ 40 ml/min/1.73 m2). Here, SST is linked to autosomal dominant polycystic kidney disease.