Cyclin D2 is a direct target gene of proto‐oncogene Myc and links growth signaling with the nuclear export of p27, contributing to the progression of the cell cycle through the G(0)‐G(1) transition.39 Several studies have suggested hypermethylation of CCND2 promoter induced the deregulated of CCND2 function in gastric cells and primary gastric carcinomas. This evidence concerns the gene CCND2 and gastric carcinoma.