MPO and metabolic dysfunction-associated steatotic liver disease: As the previous study reported, oxidative stress often occurs in the progress of hyperlipaemia and even NAFLD by regulating ROS and MPO production.48 The level of MPO and ROS in tyloxapol‐induced mice decreased significantly compared with the control group while aucubin pre‐treatment suppressed the decreasing trend indicating that high blood lipid was accompanied by the process of oxidative stress (Figure 2B).