LRP6 and tooth agenesis: Mutations in only seven genes (i.e. AXIN2 [MIM: 604,025], EDA [MIM: 300,451], MSX1 [MIM: 142,983], PAX9 [MIM: 167,416], WNT10A [MIM: 606,268], WNT10B [MIM: 601,906], and LRP6 [MIM: 603,507]) are responsible for the majority of cases with non‐syndromic tooth agenesis (Yu et al., 2018).