ETV6 and hematologic disorder: ETV6 is known to be of interest in hematopoiesis and embryonic development and of major importance in regulating megakaryocytes and platelets (Hock & Shimamura, 2017) Zang et al reported on three families with dominantly inherited thrombocytopenia and a predisposition for hematological malignancies caused by heterozygous germline ETV6 mutations (Zhang et al., 2015).