ERBB‐PI3K signaling pathway affected important cellular processes in NPC that was partially consistent with Lin et al' s study.16 Furthermore, AKT1, TP53, RAS, mTOR, and PIK3CA were recurrently present in the pathways indicated above, which were concordant with previous studies.10, 16, 17. Here, PIK3CA is linked to nasopharyngeal carcinoma.