CXCR4 and neoplasm: It is well known that blocking of SDF‐1/CXCR4 axis results in prevention or delay of tumour recurrence after irradiation by inhibiting the recruitment of CD11b+ monocytes/macrophages that participate in tumour revascularization.41 SDF‐1/CXCR4 signalling has pivotal role in mast cell (MC) recruitment in tumour tissue42 and MC produce pro‐angiogenic chemokines in response to SDF‐1,43 thus exerting important angiogenic activity.