It is well known that blocking of SDF‐1/CXCR4 axis results in prevention or delay of tumour recurrence after irradiation by inhibiting the recruitment of CD11b+ monocytes/macrophages that participate in tumour revascularization.41 SDF‐1/CXCR4 signalling has pivotal role in mast cell (MC) recruitment in tumour tissue42 and MC produce pro‐angiogenic chemokines in response to SDF‐1,43 thus exerting important angiogenic activity. Here, CXCL12 is linked to neoplasm.