SP7 and Cirrhosis: RA signalling through RARG has been shown to reverse hepatic stellate cell activation and fibrosis (51), SP7 and TP63 have been previously implicated in the regulation of VEGF-mediated angiogenesis, while PRDM1 and EBF1 have no clear connection with angiogenesis or cirrhosis reported to this date and could be novel therapeutic targets.