NPC1 and alpha 1-antitrypsin deficiency: AATD mice (Hidvegi et al., 2010), NAFLD and AFLD mice (Lin et al., 2013), FSD patients (Puls et al., 2013), AATD patient iPSC-derived hepatic cells (Choi et al., 2013), NPC1 patient iPSC-derived hepatic cells (Maetzel et al., 2014)