Previous studies show that bFGF exhibits neuroprotective activities in PD models; for instance, bFGF protected against rotenone-triggered dopaminergic cell loss in SH-SY5Y cells and enhanced survival of dopaminergic cells in human fetal tissue strands transplanted into immunosuppressed rats injected with 6-OHDA [96, 97]. This evidence concerns the gene FGF2 and Parkinson disease.