By using this unbiased approach we confirmed that, although cells with classical macrophage markers such as F4/80 show some expression of TLR3-GFP, the highest expression of TLR3-GFP was again observed in the CD103+ cDC1 Interestingly, similar findings were observed in tumor-draining lymph nodes and non-draining lymph nodes, although in both cases, GFP expression in CD11b+ cDC2 was hardly detected (Figure 1E). The gene discussed is ITGAM; the disease is neoplasm.