In this work, we used mice heterozygous for the Tlr3-EGFP allele (also known as B6-Tlr3tm2Ciphe and called TLR3-GFP knock-in mice here) to identify TLR3+ cells within the tumor that therefore represent potentially the main targets of poly A:U and consequently, the putative source of IFNβ inside the tumor. The gene discussed is TLR3; the disease is neoplasm.