PLAT and stroke disorder: In individual patient data meta-analyses of RCTs, the benefits of EVT were consistent in all prespecified subgroups of age, sex, initial stroke severity score, site of vessel occlusion, presence of tandem occlusion, extent of initial early ischemic changes on computed tomography (CT), intravenous tissue plasminogen activation (tPA), and onset-to-randomization time (26, 27).