PCSK9 and familial hyperaldosteronism: A previous systematic review (Jiang et al., 2015) collected 80 reports about FH-related mutations in Chinese populations and showed that major variants were mapped to three genes, namely, LDLR, APOB and PCSK9. As expected, among these variants, mutations in the LDLR gene (>80%) were most often reported, and 30 of these mutations were considered novel variants.