Treatment with deferiprone led to a decrease in iron accumulation not only in the murine model SOD1 G86R, but also in ALS patients where a significant decrease in iron concentration was observed in the cervical spinal cord, medula oblongata and motor cortex after 12 months of treatment, but the first visible signs were already seen after 3 months. Here, SOD1 is linked to amyotrophic lateral sclerosis.