Postmortem research conducted on human brains showed that a significant increase of iron deposition was observed in the claustrum, caudate nucleus, globus pallidus, thalamus, and subthalamic nucleus of the FTLD-FUS and FTLD-TDP groups, while in the ALS one, the iron increase was only observed in the caudate and the subthalamic nuclei. The gene discussed is FUS; the disease is amyotrophic lateral sclerosis.