We found that morin is able to downregulate LMW-PTP levels in Mec-1 cells (Fig. 1b) and that treatment with morin is able to increase Mec-1 cell sensitivity to apoptosis induced by fludarabine or ibrutinib, two drugs currently used in CLL treatment (Fig. 3). This evidence concerns the gene ATR and B-cell chronic lymphocytic leukemia.