CRP and peripheral arterial disease: In the multi-variable adjusted analysis, Lp-PLA2 activity (HR 1.33; 95% CI 1.17–1.52), Lp-PLA2 mass (HR 1.20; 95% CI 1.05–1.37), and CRP (HR 1.55; 95% CI 1.36–1.76) were all independently associated with incident PAD (Table 2).