In the current study, we found for the first time the stable expression of the cell adhesion molecules CD54/ICAM-1, CD58/LFA-3 and CD321/JAM-A on iPSC-cardiomyocytes, and a reduction of the expression levels of these cell adhesion molecules in hiPSC-CMs induced by serum from patients with myocardial infarction. Here, CD58 is linked to myocardial infarction.