Conversely, pharmacological inhibition of two demethylating enzymes KDM6A (also called UTX) and KDM6B (also called JMJD3), which specifically demethylate H3K27 dimethylation (H3K27me2) and H3K27 trimethylation (H3K27me3), attenuated glomerular disease (Majumder et al, 2018). This evidence concerns the gene KDM6A and glomerular disorder.