KDM6B and glomerular disorder: Conversely, pharmacological inhibition of two demethylating enzymes KDM6A (also called UTX) and KDM6B (also called JMJD3), which specifically demethylate H3K27 dimethylation (H3K27me2) and H3K27 trimethylation (H3K27me3), attenuated glomerular disease (Majumder et al, 2018).