Our analyses involved childhood BMI and 15 adult traits (BMI, waist-to-hip ratio, waist circumference, type 2 diabetes, fasting plasma glucose, fasting plasma insulin, glycated hemoglobin, insulin secretion, insulin sensitivity, coronary artery disease, myocardial infarction, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, total cholesterol, and triglycerides) (Additional file 1: File S1). This evidence concerns the gene INS and type 2 diabetes mellitus.