The variant alleles of rs1552245 in MY01A, rs4747192 in CDH23, rs1043421 in MYO7A, rs696211 in KCNMA1, and rs471757 in GRHL2 decreased the risk for NIHL, whereas rs212769 in EYA4, rs2394795 in CDH23, rs7910544 in KCNMA1, rs3751385 in CX43, rs666026 in GRHL2, and rs7106021 in OTOG increased the risk for NIHL. The gene discussed is CDH23; the disease is noise induced hearing loss.