The screened genes in the NIHL group included CDH23, PCDH15, eyes absent 4 homolog (EYA4), MYO1A, alpha subunit of calcium-activated potassium channel (KCNMA1), and OTOG. We also found that additional seven SNPs in six genes showed marginally significant association with NIHL (P > 0.05 and < 0.1). Here, CDH23 is linked to noise induced hearing loss.