F10 and hyperinsulinemic hypoglycemia, familial, 4: Advantages of PCCs versus FFP include more rapid correction of FX deficiency due to higher FX concentration in PCCs; greater increase in other clotting factors, which may benefit patients with acquired deficiency of other clotting factors in addition to FX case of combined clotting factor deficiency; fewer complications secondary to fluid overload; and shortened preparation time since PCCs do not need to be thawed and do not require blood typing.