FGF2 and systemic inflammatory response syndrome: bFGF can inhibit the inflammatory reaction of wounds.[16,17] It may accelerate wound repair and protect the matrix.[18,19] The effects of bFGF on various biochemical changes in the inflammatory response at the molecular level can inhibit the proliferation of lymphocytes by IL-1 and IL-2, the generation of cytokines, the expression of antigen-like enhancers that are enhanced by interferon, and the expression of activator B of the complement bypass pathway induced by cytokines.[20] The alleviation of inflammation can protect burn wounds and reduce wound sepsis and SIRS.