Curcumin is considered a natural pan‐HDAC inhibitor as it can downregulate HDAC activity and suppress the expression of HDAC types 1, 2, 3, 4, 5, 6, 8, and 11 in numerous cancer cell lines.31 Resveratrol can also modulate the activity of HDACs both in vitro and in vivo. The gene discussed is HDAC9; the disease is cancer.