Previous studies have demonstrated that miR‐338‐3p could function as a tumor suppressor in GC, NSCLC and CRC.31, 32, 33 We also confirmed the anti‐carcinogenic effect of miR‐338‐3p in CRC in this study, and the function of miR‐338‐3p is inhibited after sponged by SNHG15. The gene discussed is SNHG15; the disease is neoplasm.