Twenty‐eight years ago, one study has shown that FGF‐2 at picomolar concentrations promoted cell proliferation via regulation of ornithine decarboxylase in AR4‐2J rat pancreatic cancer cell line.45 Moroever, more evidence has emerged to validate the role of FGF‐2 in pancreatic cancer. Here, ODC1 is linked to familial pancreatic carcinoma.