FGF‐7, also called as keratinocyte growth factor (KGF), is originally observed in mesenchymal cells, demonstrated that FGF‐7 might be involved in mesenchymal stimulation of epithelial cell proliferation.58 FGF‐7/KGF is frequently overexpressed in pancreatic cancer.59 KGF/FGF‐7 activated NF‐κB (nuclear factor kappa B) and subsequently induced the expression of VEGF, MMP‐9 and urokinase‐type plasminogen activator, leading to enhancement of migration and invasion in pancreatic ductal epithelial cells. This evidence concerns the gene FGF7 and familial pancreatic carcinoma.