CDH5 and hepatocellular carcinoma: EMT, the reversible dedifferentiation process of polarized epithelial cells, has been shown to play an important role in acquiring endothelial‐like properties to form vessel‐like structures in epithelial cancers.35 Meng et al36 found that Hsp90β enhanced the VE‐cadherin promoter activity by interacting with EMT‐related transcription factor Twist1 in hepatocellular carcinoma.