MC4R and type 2 diabetes mellitus: Moreover, because we did not find any differences in the total body fat content, and we have noted some trends to the lower SAT content in AA genotype men, we can hypothesize that maybe the carriers of this SNP may have a lesser subcutaneous lipid storage capacity, what can be a reason of visceral fat accumulation and it’s clinical consequences, such as metabolic syndrome [47], or the higher risk of T2DM, what has been shown for carriers of this SNP in rs1350341 near the MC4R gene [24].