Second, preswitched memory B lymphocytes in SLE expressed higher levels of the activation markers, CD80, CD95, and CD86, than in HD, as shown by Rodriguez-Bayona et al. The affinity of platelets for activated lymphocytes does not seem to be a mechanism limited to B lymphocytes since we, along with other authors, have shown that platelets also bind preferentially to activated T lymphocytes [18, 19], favoring their binding to endothelium to migrate [50, 51]. This evidence concerns the gene CD80 and systemic lupus erythematosus.