The tumor proliferation index was evaluated by the protein expression of Ki-67, which was significantly lower in the NTX-treated group than in untreated mice [control: 8.89 (IQR, 7.55–10.10) vs NTX: 5.14 (IQR, 4.63–5.75), P = 0.0209]. The gene discussed is MKI67; the disease is neoplasm.