We found that a significantly higher proportion of the genes that were differentially expressed between high hyperdiploid and ETV6/RUNX1-positive leukemias were anchor genes in both the oligo(dT) and the RiboZero RNA-seq datasets (hypergeometric test; P = 0.0139 and P = 0.00513, respectively; Supplementary Fig. 7). This evidence concerns the gene RUNX1 and leukemia.