CT55 and Rectal prolapse: Moreover, the symptom of rectal prolapse was attenuated in Ct55 knockout mice compared with the WT control (Fig. 1d), and we observed that there was a lower incidence of rectal prolapse in Ct55-deficient mice, which is 14.3% (6 out of 15) in contrast to 40% (6 out of 15) in WT mice at 60 days in our model (Supplementary Fig. 1e).