Along with this, injection of procoagulant PL into the circulation, recently shown to acutely increase coagulation in vivo (22), caused a consumptive coagulopathy and reduced AAA incidence, similar to the protective effects of either Alox deletion or factor Xa inhibition (Figs. 2 and 5 and SI Appendix, Fig. S6B and Scheme S1). The gene discussed is F10; the disease is triple-A syndrome.