Moreover, we detected LOXL1-AS1 expression in osteosarcoma cell lines and a human normal osteoblast cell line and observed that levels of LOXL1-AS1 expression in osteosarcoma cell lines (MG63, U2OS, Saos-2, and HOS) was profoundly higher than human normal osteoblast cell line (hFOB1.19) (P<0.001, Figure 1B). Here, LOXL1 is linked to osteosarcoma.