For estimating the clinical significance of LOXL1-AS1 expression in osteosarcoma, all cases in this research were classified into high LOXL1-AS1 expression group (n=63) and low LOXL1-AS1 expression group (n=63) in accordance to the median value of LOXL1-AS1 expression. The gene discussed is LOXL1; the disease is osteosarcoma.