VEGFA and neoplasm: Further, VEGF-siRNA/RGD nanodiamond was prepared by conjugating Arg-Gly-Asp-Ser peptide and VEGF-siRNA to nanodiamond delivery particles by Cui et al. VEGF-siRNA complexes were used in antiangiogenic gene therapy to inhibit tumor growth through the downregulation of the expression of vascular endothelial growth factor.