IL13 and major depressive disorder: In a similar context, anti-inflammatory cytokines could play distinct roles in mood-associated disorders, as suggested in recent studies that show a correlation between Th2-related IL-13/IL-9 cytokine concentrations and the depressive Edinburgh Postnatal Depression Scale (EPDS) score; whereas IL-13 and IL-10 cytokine concentrations correlated with anxiety symptoms in pregnant women during mid-pregnancy [30].