MEB-Med8A is a Group 3 medulloblastoma cell line, with strong associations with classical Group 3 characteristics, such as myc amplification and pvt1-myc fusion [39, 40], whereas the grouping affiliation of D283-MED is more controversial, with a lack of myc amplification pointing towards Group 4 [37, 38]. The gene discussed is PVT1; the disease is medulloblastoma.