CD200 and fetal growth restriction: Some have reported a mitochondrial implication in placenta by transcriptomic analysis,30 metabolic disarrangements in serum of IUGR infants31 or less mitochondrial DNA (mtDNA) in cytotrophoblast cells.18 Mandó et  al have also described lower MRC mRNA expression in cytotrophoblast cells but no alterations at protein level.18 While others found altered MRC enzymatic activities in human placental homogenate.32