Furthermore, we found that expression of Caspase 8 was negatively correlated with tumour‐node‐metastasis (TNM) stages in tissues with high p62 expression Figure 1D. In addition, high Caspase 8 expression was associated with less relapse risks in patients who overexpressed p62 (Figure 1E). The gene discussed is SQSTM1; the disease is neoplasm.