For example, proteasome inhibitor MG132 was reported to promote apoptosis of U87 cells through p62 accumulation and metastatic and recurrent tumour tissues express low levels of p62.2, 3, 4 Our previous study found that p62 was involved in regulating the SKOV3 ovarian cancer cells sensitivity to chemotherapy through NF‐κB signalling and ubiquitin clearance.5, 6 Together these results indicate p62 has multi‐faced functions and plays complex roles in determining the outcome of tumourigenesis. The gene discussed is SQSTM1; the disease is ovarian cancer.