We analyzed the relationship between the kinetic parameters measured on the dynamic PET/CTs and the known predictive and prognostic factors (i.e. clinical T and clinical N stages; histological type; nuclear grade; ER, PR and HER2 status, Ki-67 LI and tumor subtype) in pre-therapy core-biopsies (Table 2). The gene discussed is MKI67; the disease is neoplasm.