Moreover, exercise promotes neuronal survival and improves vascular activity and cerebral blood flow post-induced stroke in animal models, increasing vascular endothelial growth factor (VEGF) and insulin-like growth factor (IGF), which are pivotal in cerebral vasculature angiogenesis (Dornbos et al. 2013; Carro et al. 2000; Cotman et al. 2007; Tang et al. 2010). The gene discussed is VEGFA; the disease is Stroke.