In patients with gastric cancer, SRCs are associated with poor prognosis.3 Recent studies have shown that response to nCT is poor in patients with SRC gastric cancer, and the benefit of nCT in this type of tumor is debated.4,5 SRC histology in patients with EAC may also be used as a predictor of prognosis and response to treatment. This evidence concerns the gene SRC and gastric cancer.