NCOA2 and breast cancer: The copy number of the NCOA2 gene was analyzed by using the cBioPortal online tool (www.cbioportal.org) and found to be frequently amplified in four independent breast cancers datasets [METABRIC, Nat Commun 2016; BRCA, INSERM 2016; TCGA Pancancer Atlas; The Metastatic Breast Cancer (MBC) Project] (27–29), varying from 5 to 14% amplification (Figure 1A).