For the CKD rats treated with JPYS extract, the decreased levels of RBC, Hb, and HCT were obviously restored, from 7.4 to 8.5×1012/L (P=0.03) in RBC, 12.4 to 13.9 g/dL (P=0.02) in Hb, and 38.9 to 45.6% (P=0.04) in HCT. This evidence concerns the gene GSTM1 and chronic kidney disease.