ALB and neoplasm: Figure 3(a) shows ultrasound measurements demonstrating that PNA increased the perfusion rate of the hypoxic core of 4T1 flank tumors compared to the tail vein infusion of HSA.  Figure 3(b) shows the reperfusion kinetics of the microbubble burst by the ultrasound. Figures 3(c) and 3(d) illustrate the difference of the perfusion volume of the flank tumor detected by the microbubble technique from tail vein infusion of HSA versus PNA, respectively.