Since the pro-inflammatory cytokines, IFN-γ, and IL-17 have been shown to be key effector molecules in many, but not all EAE models (15, 16, 45–48), we first examined the kinetics of IFN-γ and IL-17 in animal models for PP-MS, using two mouse strains. The gene discussed is IL17A; the disease is myeloid sarcoma.