The MRZR-1 (AI positive when ≥1.5) was positive in 80.9% of ANA-positive MS-patients and 20% of RDwCNS-patients (p < 0.0001), the MRZR-2 was positive in 54.4% compared to 12.5% in RDwCNS (p < 0.0001) (Figure 1). The gene discussed is BTG3; the disease is myeloid sarcoma.