GRB2 and myeloid sarcoma: As mentioned above, the genes GRB2 and DOCK2 are also within the ± 500 kb region of MS risk SNPs (Figures S4B,C), and VSE regions around IL6R, PRKCD and GRB2 are also enriched in the GO term: “positive regulation of immune system process” (Figure 1D and Supplementary File 1).